Catalogs and product finders. Chim. In addition to the Thermodynamics Research Center CHCl. Molecular Weight 181.45. (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. The lower energy states of HeH + is reached when product formed are He + H +.. 12/14/2020, Occupational Safety & Health Administration, Occupational Safety and Health Administration, Outreach Training Program (10- and 30-hour Cards), OSHA Training Institute Education Centers, Severe Storm and Flood Recovery Assistance. Chamblee, GA 30341-3717 - 298. The Preparation of 2,3,5-Trichlorophenoxyacetic acid (2,4,5-T), NIST subscription sites provide data under the (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Chem. : Washington, D. C., 1955. Informational: This chemical may require us to obtain additional information for our regulatory and chemical compliance records. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. Biologically Active Compounds | All rights reserved. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein ; Hopke, E.R., However, NIST makes no warranties to that effect, and NIST CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . A general reaction search Synonyms. The LD50 (oral, rats) is 756mg/kg. uses its best efforts to deliver a high quality copy of the Organic and Inorganic Compounds, It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: Jones, A.H., Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Email: Contact CDC-INFO. NIST subscription sites provide data under the Colorless liquid or crystalline solid (below 63F) with an aromatic odor. 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. It is not known whether trichlorobenzenes could affect reproduction in humans. It appears that your browser has JavaScript disabled. Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., endstream endobj 27 0 obj <>stream (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. 0.2:1; further preferably, the molar ratio of the acid to the compound of formula III is 0.2:1. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U If required, we will contact you for this information once your order is placed. NIST Standard Reference [all data], Rohc, Ruzicka, et al., 1999 ; 1.) 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. Your institution may already be a subscriber. Thermodynam., 1982, 14, 303-308. Physical Properties of Chemical Compounds, Advances in Chemistry Series No. Eng. What Generation is Your Sterility Testing Pump? in these sites and their terms of usage. Fast, safe transfer of plates to isolator. Dreisbach, R.R., Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. in these sites and their terms of usage. They help us to know which pages are the most and least popular and see how visitors move around the site. 1,2,4-Trichlorobenzene for synthesis. Standard Reference Data Act. 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification Cosolvents are often needed to dissolve these chemicals in cell culture medium. the Your contract pricing may differ. [all data], Petit and TerMinassian, 1974 Exit. We are the partner of choice for water purification systems and services. The interactive spectrum display requires a browser with JavaScript and SRD 103b Thermo Data Engine (TDE) for pure compounds, intended to imply recommendation or endorsement by the National Notice: This spectrum may be better viewed with a Javascript Merck KGaA, Darmstadt, Germany, 2014. form is shall not be liable for any damage that may result from PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. However, NIST makes no warranties to that effect, and NIST 1,2,4-Trichlorobenzene. 2. D0-(]PlAm*R5&{b>#7b]'Ddm\Bj. available from the NIST/EPA/NIH Mass Spectral Library. Ind. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure. The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. Chem., 1981, 85, 1490. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. Data Program, but require an annual fee to access. [all data], van de Lande, 1932 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. endstream endobj 26 0 obj <>stream How likely are trichlorobenzenes to cause cancer? Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), [all data], Wilhelm, Inglese, et al., 1982 and HTML 5 enabled browser. Price (EUR) Price: 98,60. Phone: 1-800-CDC-INFO 888-232-6348 (TTY) Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. A-006. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact: Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. 10. [all data], Jondorf and Williams, 1958 How can trichlorobenzenes affect children? Transl. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. other in their chemical structure. Database and to verify that the data contained therein have Go To: Top, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. Formula. Watch, learn and engage with us. How can families reduce their risk for exposure to trichlorobenzenes? Properties Grade anhydrous CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. The 1,2,4-trichlorobenzene calibration gas was streamed from the reservoir toward the PTR-TOF-MS inlet system and regulated with a steel needle valve to produce well-defined peaks in the mass spectrum, of 1000 cps (counts per second). This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. Chem. H315: Causes skin irritation. This Website requires your browser to be JavaScript enabled. Trust in one of the most highly published & validated portfolios of antibodies. Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata Contact Us to ask a question, provide feedback, or report a problem. This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. All information these cookies collect is aggregated and therefore anonymous. 1,2,4-Trichlorobenzene is produced in large Physical description. About Us | Follow the links above to find out more about the data People who manufacture or work with trichlorobenzenes can be exposed to them. Thank you for taking the time to confirm your preferences. All Rights Reserved. Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 This may be a synopsis of the full weight-of-evidence narrative. unsym-trichlorobenzene; 1,2,4-trichlorobenzol. Medium. View image of digitized 1,2,4-Trichlorobenzene, NIOSH: Pocket Guide to Chemical Hazards - Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. [all data], Rohc, Ruzicka, et al., 1998 NOAA: CAMEO Chemicals - #=0!w}S&!T7U/9s$5U]O~K%~ed>7ueY?*us6/Wn]/LfSG{q&^{Wz;Ec' SUvE9d"Mxx*?~:YfDK(@+hwh'3hbc^.P)d!9(@ !pqp888 j"Si)rZr Physical Properties. J. Chem. with the development of data collections included in There are no studies of cancer in people exposed to trichlorobenzenes. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. The product quantity has been adjusted. Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. [all data], Platonov and Simulin, 1985 J. Phys. High levels of trichlorobenzenes are often detected in fish or other species living in contaminated waters because trichlorobenzenes can accumulate in fatty tissues. 1000. This ToxFAQsTM information is taken from the 2014 Toxicological Profile for Trichlorobenzenes produced by the Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services in Atlanta, GA. Journals | Physical Properties. What happens to trichlorobenzenes when it enters the environment? Res. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. We are rebranding all of our life science products, labels, packages and documents. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, by the U.S. Secretary of Commerce on behalf of the U.S.A. Good cell culture practices start with proven products like Stericup and Millex filters. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 The following components were used in generating the plot: Additonal code used was developed at NIST: H315: Causes skin irritation. BS - Robert L. Brown and Stephen E. Stein InChI=1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H<, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, CDC - NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=1,2,4-Trichlorobenzene&oldid=1119441075, This page was last edited on 1 November 2022, at 16:19. Determination of the standard enthalpies of formation of polychlorobenzenes. People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have higher exposure to these substances. 1,2,4-Trichlorobenzene MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. Last Updated: 05/01/1992. A new class of spectrophotometers for water analysis. the library and The half-life (the time it takes for 50% of the compound to degrade) of trichlorobenzenes in air is about 1 month. However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. . Moreover, the free concentration Get all suppliers and price by the below link: Home | Please see the following for information about Enter the desired X axis range This table shows how each list refers to the substance. View plot Database and to verify that the data contained therein have SRD 103a Thermo Data Engine (TDE) for pure compounds. been selected on the basis of sound scientific judgment. It is useful as a high-temperature solvent, e.g. HTML 5 canvas support. T = temperature (K). Sublimation Pressure Data for Organic Compounds., Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director Articles of 1,2,4-Trichlorobenzene are included as well. 1,2,4-Trichlorobenzene for synthesis. such sites. Future versions of this site may rely on 120-82-1. Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) Agency for Toxic Substances and Disease Registry Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. [all data], Schlosser, Marzi, et al., 2001 1 x 10 -2. Soc. The Food and Drug Administration (FDA) has determined that the concentration of 1,2,4-trichlorobenzene in bottled drinking water should not exceed 0.07 mg/L. Yan, H.; Gu, J.; An, X.; Hu, R., Technology, Office of Data The reaction is as follows: HeH + He + H +. Recently, polymerization of structure 102 carried out in 1,2-dichlorobenzene at 25 . The purpose of the fee is to recover costs associated and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. Institute of Standards and Technology, nor is it intended to imply NIST Standard Reference Thermochim. Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. Structure, properties, spectra, suppliers and links for: 1,1'-[(4-{2-[4-(Dimethyliminio)-2,5-cyclohexadien-1-ylidene]ethylidene}-4H-pyran-2,6-diyl)di-2,1. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., Recl. * [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. HTMO1WHCH=bJT;q&a2v=|W~^b6Lmr"{OL{yP7?Nk.TTA(#` FxS*Ah,YjjKSTF9x:q0ffvn 0htoh D"od,,76=:(x However, this was based on studies conducted prior to 1990; newer information has not been evaluated. H410: Very toxic to aquatic life with long lasting effects. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and There is almost no information about health effects of trichlorobenzenes in humans. [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. Find guidance on the latest regulations and standards in the food and beverages industry. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. HU0~]$'RWS`HlE*'G8 . spectrum (can be printed in landscape orientation). Imaging flow cytometry makes it possible. The . Chem. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. H410: Very toxic to aquatic life with long lasting effects. . displays seen below. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. C6H3-1,2,4-(Cl)3. Training programs and seminars designed for you. Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. following TRC products: Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. T = 297 to 454 K. Value is unsmoothed experimental datum. It is a derivative of benzene with three chloride substituents. Based on data from 279. It's important you understand this information because this substance may harm you. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses.