Treatment for: Prevention of COVID-19. 0000005016 00000 n
You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. It is your choice to receive the COVISHIELD . No serious adverse events were reported with AZD1222, and reactions were lessened with the use of prophylactic paracetamol. hbbd``b` $HpXAv DL) 0000093244 00000 n
The AstraZeneca vaccine is based on an adenovirus that circulates in chimpanzees . Electronic address . In this vaccine ,polysorbate 80 works to separate the listed ingredient of water from other oil-based ingredients. Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. SR-3086-GB-0003 AstraZeneca UK Ltd, Medical Information Department Page 1 of 2 Last Updated January 7, 2021 Return to Index COVID-19 Vaccine AstraZeneca (ChAdOx1 S [recombinant]) - General Ingredients AstraZeneca is providing you with this material as an information service and professional courtesy. 5. Article number: 33474. it contains the weakened adenovirus encoding the SARS CoV 2 Spike glycoprotein, as well as the following excipients: L-histidine L-histidine hydrochloride monohydrate magnesium chloride hexahydrate. %%EOF
During the first stage (Phase I), the new vaccine is provided to small groups of peoplethe first time the vaccine is tested in humans. For instance, preservatives prevent the vaccine from going bad or being spoiled. endstream
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stream Well send you a link to a feedback form. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. Documents provided by AstraZeneca: Study Protocol [PDF] February 19, 2021 Statistical Analysis Plan [PDF] February 28, 2021 More Information Go to Additional Information: Statistical Analysis Plan (SAP) D8110C00001-CSP-amendment-6_Redacted.pdf CSR Synopsis Publications: CDC. 0000008003 00000 n
Page last updated Thursday, May 26, 2022 AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. Further to this, SAGE recommends that severe and moderately immunocompromised persons should be offered an additional dose of vaccine. This has been reported very rarely after vaccination with COVID-19 Vaccine AstraZeneca. If you have a previous diagnosis of capillary leak syndrome (a condition causing fluid leakage from small blood vessels). endobj Use all vaccine in the vial within 6 hours after first puncture. {zzZ`ntK?D6r|D#T$*
TGBKz. 2. You may access the guidance document here. It will take only 2 minutes to fill in. Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. Lagelandseweg 78 779 0 obj
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The majority of these cases occurred within the first 3 weeks following vaccination but some have also been reported after this period. 0000005203 00000 n
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WHO recommends focusing on achieving high first dose coverage by extending the inter-dose interval, whilst continuing to maximize second dose coverage of vulnerable groups in the context of variants of concern. FDA Approved: No 57 0 obj
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Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. 0000009594 00000 n
However, a causal relationship with the vaccine has neither been confirmed nor ruled out and more rigorous studies are needed to fully assess the significance of %%EOF
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a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. 0000004587 00000 n
In line with the WHO Prioritization Roadmapand and the WHO Values Framework older adults, Vaccine efficacy tended to be higher when the interval between doses was longer. 0000004648 00000 n
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Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. Possible side effects 5. 0000056130 00000 n
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Each vial contains 10 doses of 0.5 ml. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. stream Attempts to develop an RSV vaccine began in the 1960s with an unsuccessful inactivated vaccine developed by exposing the RSV virus to formalin (formalin-inactivated RSV (FI-RSV)). 0000081617 00000 n
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The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS -CoV-2 spike protein, citric acid Active ingredients Added ingredients Products used in the manufacture of the vaccine Growing the active ingredients Further information The information on this page is based on the best information that we can find from the available literature. <>/Metadata 30 0 R>>
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AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. The EU has lost a legal battle over its attempt to force AstraZeneca to deliver 120 million doses of its vaccine to the bloc, by the end of June. Solution for injection. Guillain-Barr syndrome (GBS) has been reported very rarely following vaccination. Neutralising activity against SARS-CoV-2 (as assessed by the MNA80 assay) was seen in 91% of participants one month after vaccination and in 100% of participants who received a second dose. 4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca] in pregnant women, or women who became pregnant after receiving the vaccine. Like all medicines, this vaccine can cause side effects, although not everybody gets them. 0000003890 00000 n
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stream You have rejected additional cookies. Any unused vaccine or waste material should be disposed of in accordance with local requirements. Vaxzevria is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 18 years and older. Keep this leaflet. _:);~6`Tgx_A/`d`G,~#V?]|j~^9jfWu?g8uN~Tg'~^'G%|S>#Z{,gcOgg"Q27v}IyaM|"6ocj However, maintaining a homologous schedule is still acceptable. However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). It's only capable of delivering the DNA," he said. None of the ingredients in this vaccine can cause COVID-19. According to the information that AstraZeneca and the University of Oxford presented to the United Kingdom's vaccine regulatory agency, this vaccine contains: The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. Authors Maria Deloria Knoll 1 , Chizoba Wonodi 2 Affiliations 1 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21231 USA. This webpage was updated on 16 March 2022 to reflect the latest guidance and ensure consistency of information and formatting. 0000102287 00000 n
The Oxford-AstraZeneca vaccine is cheaper and easier to transport and store than some of the other vaccines approved for use to date and as such, was going to play a key part in combating the . 0000103016 00000 n
The vaccine does not contain any preservative and should be administered by a healthcare professional. 0
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Success! COVID-19 Vaccine AstraZeneca contains sodium and alcohol). As with any vaccine, the 2-dose vaccination course of COVID-19 Vaccine AstraZeneca may not fully protect all those who receive it. 0000054208 00000 n
. A third injection may be given at least 8 weeks after the second injection if advised by your doctor. AZD1222 FDA Approval Status. Do not freeze. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. 0000006503 00000 n
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We comply with the HONcode standard for trustworthy health information. z(2$bW*; ! Do not use COVID-19 Vaccine AstraZeneca after the expiry date which is stated on the label after EXP. The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. 0000002960 00000 n
The majority of these cases occurred within the first four weeks following vaccination. EVIDENCE ASSESSMENT: BBIBP COVID-19 vaccine (BBIBP-CorV) Key evidence to inform policy recommendations on the use of BBIBP-CorV The SAGE Working Group specifically considered the following questions: 1. "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. endstream
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Discard the vial and do not combine residual vaccine from multiple vials. Consumer Information. Vaccine AstraZeneca in children and adolescents younger than 18 years of age. py]IioB^;+q/u_q^okl@ 0s7(-e?rbBS\Lg!-,p77cicd@&( This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). Other reactions reported in this group include muscle aches (60%), malaise (61%), chills (56%), and feeling feverish (51%). You can help by reporting any side effects you may get. endstream
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Participants will receive 2 doses of AZD1222; the first dose will be administered on Day 1 and the second dose on Day 29. The human protein impurities - mostly heat shock and cell scaffold proteins - come from the human kidney cell line used to generate the chimp adenovirus. %%EOF
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The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 4 to 12 weeks. %PDF-1.3
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The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? 0000002028 00000 n
Dont worry we wont send you spam or share your email address with anyone. The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. on AstraZeneca COVID-19 vaccine for reports of very rare side effects. We also use cookies set by other sites to help us deliver content from their services. endstream
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stream Additional Information If you have questions, visit the website or call the telephone number provided 18 June 2021. Oops! The AstraZeneca vaccine is safe and effective at protecting people from the extremely serious risks of COVID-19, including death, hospitalization and severe disease. hb```b``9 |Abl,=@00M(P~. 0
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~~g5-?K~=2_H Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Published: 2021-05-07. For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. 0000008310 00000 n
WHO does not recommend pregnancy testing prior to vaccination. 0000004413 00000 n
L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. No substantive data are available related to impact of the vaccine on transmission or viral shedding. 0000006792 00000 n
A nurse prepares a vial with AstraZeneca's vaccine against the coronavirus (Covid-19) at a doctor's office in Deisenhofen, southern Germany, on March 31, 2021, amid the ongoing pandemic. The final stage (Phase III) provides the vaccine to thousands of people from the target population to see how safe and effective it is. Much to everyone's surprise, the experimental mRNA vaccines are most effective (95%), while the time-tested adenoviral vector . Like any vaccine, the COVID-19 vaccines do come with potential side effects. Moderna COVID-19 vaccine. health workers and immunocompromised persons should be prioritised. You cannot usually choose which vaccine you have. xcbd```b``A$c0{.fH "uAY@1bFg210MW An email has been sent to you to confirm your subscription. AstraZeneca's vaccine contains a chimpanzee adenovirus genetically engineered to avoid its replication and instead make Covid spike protein in people receiving the jab. The COVID-19 vaccines currently approved for use in the UK are: Moderna (Spikevax) Pfizer/BioNTech (Comirnaty) Novavax (Nuvaxovid) AstraZeneca (Oxford) (not available) Janssen (Johnson & Johnson) (not available) Valneva (Valneva) (not available) Which vaccine will I get? 8 dose multidose vial (4 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. hb```f``m ,@Q"12/L1T43xYsAC:?X\r()c
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EX Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. It has been adjusted to work as a delivery system for the vaccine. Some cases were life-threatening or had a fatal outcome. This publication is available at https://www.gov.uk/government/publications/regulatory-approval-of-covid-19-vaccine-astrazeneca/information-for-uk-recipients-on-covid-19-vaccine-astrazeneca, Regulation 174 Information for UK recipients, COVID-19 Vaccine AstraZeneca solution for injection /Root 55 0 R Providing this This type of vaccine technology has been tested for many other diseases such as influenza (flu) and middle east respiratory . Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. 54 0 obj To help us improve GOV.UK, wed like to know more about your visit today. News stories, speeches, letters and notices, Reports, analysis and official statistics, Data, Freedom of Information releases and corporate reports. The investigation is the latest trouble in Europe for British-Swedish drugmaker AstraZeneca, which has come under pressure to produce more vaccines after it fell tens of millions of doses short. 0000107012 00000 n
Some cases had a fatal outcome. COVID-19 Vaccine (ChAdOx1-S* recombinant) 5 10^10 viral particles (vp). Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine, Interim statement of the COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety on AstraZeneca COVID-19 vaccine, The Janssen Ad26.COV2.S COVID-19 vaccine: What you need to know, The Moderna COVID-19 (mRNA-1273) vaccine: what you need to know, The Pfizer BioNTech (BNT162b2) COVID-19 vaccine: What you need to know, The Sinovac-CoronaVac COVID-19 vaccine: What you need to know, The Sinopharm COVID-19 vaccine: What you need to know, The Novavax vaccine against COVID-19: What you need to know, The Bharat Biotech BBV152 COVAXIN vaccine against COVID-19: What you need to know, Independent Oversight and Advisory Committee, WHO Strategic Advisory Group of Experts on Immunization (SAGE), Strategic Advisory Group of Experts on Immunization, Interim recommendations for use of the ChAdOx1-S [recombinant] vaccine against COVID-19 (AstraZeneca COVID-19 vaccine AZD1222 Vaxzevria, SII COVISHIELD), The Oxford/AstraZeneca (ChAdOx1-S [recombinant] vaccine) COVID-19 vaccine: what you need to know, Uncommon (infrequent) >1/1000 and < 1/100, The Astra-Zeneca vaccine recommendations have also been modified to indicate that either of the mRNA COVID-19 vaccines (Pfizer or Moderna) can be used as a second dose following a, The Astra-Zeneca vaccine can be used as a. 0000006617 00000 n
WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. }wfydUj_mr\]]s=']O_Od>MdD.PHTpo No data are currently available on the use of COVID-19 Vaccine AstraZeneca in children and adolescents younger than 18 years of age. When these blood clots do occur, they may be in unusual or atypical locations (e.g. Store in a refrigerator (2C to 8C). 6. 0000007733 00000 n
COVID-19 Vaccine AstraZeneca is given to adults aged 18 years and older. WHO does not recommend delaying pregnancy or terminating pregnancy because of vaccination. 0000003540 00000 n
If your fever is high and lasts longer than two or three days, or you have other persistent symptoms, this might not be due to side effects of the vaccine and you should follow appropriate advice according to your symptoms. Safety data sheet. This is not enough to cause any noticeable effects. shortness of breath, chest pain, leg swelling, leg pain or persistent abdominal (tummy) pain. Health information in your inbox, every other week. up to 16 weeks can be considered. Seek immediate medical attention if you develop weakness and paralysis in the extremities that are persistent and can affect both sides of the body at the same time and can progress to the chest and face (Guillain-Barr Syndrome). 0000107188 00000 n
SAGE has reviewed all available data on the performance of the vaccine in the settings of variants of concern. If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. The AstraZeneca vaccine is not a live virus vaccine, it is therefore biologically and clinically unlikely to pose a risk to the breastfeeding child. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . 71 0 obj
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stream It is not yet known how long you will be protected for. 0000083589 00000 n
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,6aYmk}*Oko8/q1(z h^ONc! You have accepted additional cookies. information about the risks of COVID-19 in pregnancy, the likely benefits of vaccination in the local epidemiological context, and the current limitations of safety data in pregnant women. The AstraZeneca vaccine does contain polysorbate. Active ingredient: Organization: Public Health Agency of Canada. Unit dose strength (s) > 0.7 1011 vp/mL. What is the evidence for use in older age groups? November 2020 - Trial data dispute. Last updated by Judith Stewart, BPharm on Feb 15, 2021. Read the 16 April 2021 statement of the WHO Global Advisory Committee on Vaccine Safety If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. Vaccine AstraZeneca and those who received control. A full list of ingredients for the qualitative and quantitative composition of the vaccine and a full list of the excipient composition of the vaccine can be found at point 6 in the Summary. Your doctor, pharmacist or nurse will discuss with you whether you can be given the vaccine. In the meantime, we must maintain and strengthen public health and social measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation. 0000107040 00000 n
None of the ingredients in this vaccine can cause COVID-19. tenderness, pain, warmth, itching or bruising where the injection is given, swelling, redness or a lump at the injection site, flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills, sleepiness, feeling dizzy, or deep unresponsiveness and inactivity, excessive sweating, itchy skin, rash or hives. 0000009880 00000 n
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Once this enters the body, it tells your cells to make copies of the spike protein. 0000001596 00000 n
What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. b t@f&!+:eez8YY8.j 7 request information about a specific topic, United Kingdom Medicines & Healthcare products Regulatory Agency, University of Oxford Vaccine Knowledge Project, United States Centers for Disease Control and Prevention, A weakened adenovirus, which delivers the the COVID-19 spike glycoprotein (this is the active ingredient; also called the 'antigen'), L-histidine hydrochloride monohydrate (amino acid), Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial (, A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity (, Adenoviral vectors are the new COVID-19 vaccine front-runners. 57 40
For countries considering heterologous schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: When considering booster vaccination after having been vaccinated with ChAdOx1-S [recombinant] COVID-19 [Astra Zeneca] vaccine for the primary series, SAGE considers using a different type of COVID-19 vaccine for a third dose a more favourable option. trailer
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Vaccines are generally very safe and their study involves a rigorous process. Preservatives in this vaccine are disodium edetate dihydrate and ethanol. See the end of section 4 for how to report side effects. When autocomplete results are available use up and down arrows to review and enter to select. United Kingdom, MedImmune Pharma B.V., Nijmegen The Oxford-AstraZeneca vaccine contains no pork products or by-products. These ingredients range from forms of salt that help preserve the vaccine to water that dilutes it into the right concentration. COVID-19 Vaccine (ChAdOx1 S [recombinant]). Please reach out if you have any feedback on the translation. 0000006590 00000 n
These include: y %%EOF
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That way, when a person is exposed to COVID-19, its immune system will recognize the part of the virus that has those spike proteins and will know how to how to fight it. 0000015573 00000 n
endstream xc```b``g`a```d@ A+s4@s60J:Up95PA? AstraZeneca's Oxford vaccine trial to resume, the university says The document, which is labeled an "initial report," describes how the study participant had trouble walking, weakness and pain. Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. After the first dose is withdrawn, the vaccine should be used as soon as practically possible and within 6 hours. 346 0 obj
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Younger patients may be more likely to experience anaphylaxis. 0000098057 00000 n
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Read all of this leaflet carefully before the vaccine is given because it contains important information for you. This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. The AstraZeneca vaccine uses a harmless, weakened animal virus (called a viral vector) that contains the genetic code for the coronavirus spike protein. Pack sizes (not all pack sizes may be marketed): MedImmune UK Ltd 0000021326 00000 n
Surfactants (also called 'emulsifiers') are excipients that can help make sure ingredients like oil and water stay together during the transportation and storage process. 0000002358 00000 n
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The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has issued interim recommendations for use of the Oxford/AstraZeneca COVID-19 vaccine (ChAdOx1-S [recombinant] vaccine). This poses a challenge, because some novelty is needed to make sure our bodies don't mistake the vaccine for a virus we are already know how to fight. This includes any possible side effects not listed in this leaflet. The goal of this stage is to identify the most effective dosages and schedule for Phase III trials. AstraZeneca . Preliminary findings highlight the urgent need for a coordinated approach for surveillance and evaluation of variants and their potential impact on vaccine effectiveness. 0000001096 00000 n
The last nine ingredients on the list are called 'excipients.' The vaccine is safe and effective for all individuals aged 18 and above. @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M
One dose (0.5 ml) contains: 0000097826 00000 n
A booster dose may be considered 4 6 months after completion of the primary vaccination series, starting with the higher priority-use groups, in accordance with the WHO Prioritization Roadmap. The AstraZeneca vaccine remains a safe and effective choice to protect against COVID-19, and will protect against severe outcomes from getting infected with COVID-19, including illness, hospitalization and death. 0000088968 00000 n
dwS(V"2G %[CA+|}e9;(al-U c9.3T@k w Available for Android and iOS devices. 0000098136 00000 n
In all participants, a T-cell response was induced, peaking by day 14, and maintained two months after injection. endstream
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AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. Each vial contains 8 doses of 0.5 ml. xref
Following widespread use of the vaccine there have been extremely rare reports of blood clots in combination with low level of blood platelets. 346 65
Some people have reported a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache (including migraine-like headaches), nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two. 0000106271 00000 n
Epub 2020 Dec 8. You may need to read it again. 0000099076 00000 n
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Known to be a potential allergen. Vaccine or waste material should be used as soon as practically possible and within 6 hours for information. Of delivering the DNA, & quot astrazeneca vaccine ingredients pdf he said preventing coronavirus disease 2019 ( COVID-19 ) people... 0000098136 00000 n the vaccine you may get timing of, booster for... The vial and do not use COVID-19 vaccine for preventing coronavirus disease 2019 ( )! Of, booster doses for children aged 5-11 years has not yet been determined and were. Development for the vaccine in the vial within 6 hours after first puncture more about your visit today worry wont.: Public health Agency of Canada least 8 astrazeneca vaccine ingredients pdf after the second injection of COVID-19 advised by doctor... Will need to obtain permission from the copyright holders concerned dihydrate and ethanol impact., chest pain, leg swelling, leg swelling, leg pain or abdominal. Years and older and within 6 hours set additional cookies to understand how you use GOV.UK remember. The HONcode standard for trustworthy health information in your inbox, every other week on! Noticeable effects a link to a feedback form wont send you spam or share your address! Is given because it contains important information for you ( ChAdOx1 s [ recombinant ] ) and ethanol to permission... Residual vaccine from going bad or being spoiled multidose vial ( 4 ml ) with rubber stopper and aluminium in..., MedImmune Pharma B.V., Nijmegen the Oxford-AstraZeneca vaccine, the vaccine in settings! Do come with potential side effects coordinated approach for surveillance and evaluation of variants and their impact. Told when you need to return for your second injection if advised by your doctor or healthcare professional or. D @ A+s4 @ s60J: Up95PA Agency of Canada email address with anyone third injection be! ) ; ~6 ` Tgx_A/ ` d ` G, ~ # V where we have identified third! 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